Genders Gene-splicing

Gene

Meanings and phrases

gene

Pronunciation American British Australian Indian
n.
  1. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; cistron; factor

Gene Kelly

Pronunciation American British Australian Indian
n.
  1. United States dancer who performed in many musical films (1912-1996); Kelly; Eugene Curran Kelly

Gene Sarazen

Pronunciation American British Australian Indian
n.
  1. United States golfer who was first to win all four major golf tournaments (1902-1999); Sarazen

Gene Tunney

Pronunciation American British Australian Indian
n.
  1. United States prizefighter who won the world heavyweight championship by defeating Jack Dempsey twice (1898-1978); Tunney; James Joseph Tunney

X-linked gene

Pronunciation American British Australian Indian
n.
  1. a gene located on an X chromosome

Y-linked gene

Pronunciation American British Australian Indian
n.
  1. a gene located on a Y chromosome; holandric gene

dominant gene

Pronunciation American British Australian Indian
n.
  1. gene that produces the same phenotype in the organism whether or not its allele identical

gene chip

Pronunciation American British Australian Indian
n.
  1. a microchip that holds DNA probes that form half of the DNA double helix and can recognize DNA from samples being tested; DNA chip
n.
  1. a vector for delivering genes into cells; transducing vector

gene expression

Pronunciation American British Australian Indian
n.
  1. conversion of the information encoded in a gene first into messenger RNA and then to a protein
E.g.
  • changes in gene expression, changes in motility behavior).
  • This prevents even low levels of inappropriate gene expression.
  • In fish, Hox gene expression regulates mechanisms for tooth initiation.

gene linkage

Pronunciation American British Australian Indian
n.
  1. (genetics) traits that tend to be inherited together as a consequence of an association between their genes; all of the genes of a given chromosome are linked (where one goes they all go); linkage

gene mutation

Pronunciation American British Australian Indian
n.
  1. (genetics) a mutation due to an intramolecular reorganization of a gene; point mutation

holandric gene

Pronunciation American British Australian Indian
n.
  1. a gene located on a Y chromosome; Y-linked gene

homeobox gene

Pronunciation American British Australian Indian
n.
  1. one of various similar homeotic genes that are involved in bodily segmentation during embryonic development; homeobox

homeotic gene

Pronunciation American British Australian Indian
n.
  1. one the genes that are involved in embryologic development

jumping gene

Pronunciation American British Australian Indian
n.
  1. a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole); transposon

lethal gene

Pronunciation American British Australian Indian
n.
  1. any gene that has an effect that causes the death of the organism at any stage of life

modifier gene

Pronunciation American British Australian Indian
n.
  1. a gene that modifies the effect produced by another gene; modifier

mutant gene

Pronunciation American British Australian Indian
n.
  1. a gene that has changed so that the normal transmission and expression of a trait is affected

operator gene

Pronunciation American British Australian Indian
n.
  1. a gene that activates the production of messenger RNA by adjacent structural genes

recessive gene

Pronunciation American British Australian Indian
n.
  1. gene that produces its characteristic phenotype only when its allele is identical

regulator gene

Pronunciation American British Australian Indian
n.
  1. a gene that produces a repressor substance that inhibits an operator gene; regulatory gene

regulatory gene

Pronunciation American British Australian Indian
n.
  1. a gene that produces a repressor substance that inhibits an operator gene; regulator gene

repressor gene

Pronunciation American British Australian Indian
n.
  1. gene that prevents a nonallele from being transcribed

structural gene

Pronunciation American British Australian Indian
n.
  1. a gene that controls the production of a specific protein or peptide

suppresser gene

Pronunciation American British Australian Indian
n.
  1. a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene); suppressor; suppresser; suppressor gene

suppressor gene

Pronunciation American British Australian Indian
n.
  1. a gene that suppresses the phenotypic expression of another gene (especially of a mutant gene); suppressor; suppresser; suppresser gene
E.g.
  • Studies suggest this is a tumor suppressor gene.
  • It can behave as a tumour suppressor gene.
  • PTEN is a tumor suppressor gene that is involved in cellular signalling.
n.
  1. a gene that disposes normal cells to change into cancerous tumor cells; oncogene
n.
  1. a suppressor gene that blocks unscheduled cell division
E.g.
  • Studies suggest this is a tumor suppressor gene.
  • PTEN is a tumor suppressor gene that is involved in cellular signalling.
  • It is caused by genetic mutations in the Von Hippel–Lindau tumor suppressor gene.

gene encodes

Pronunciation American British Australian Indian
E.g.
  • This gene encodes a homolog of Drosophila prickle.
  • This gene encodes a member of the apyrase protein family.
  • This gene encodes a member of this family.

gene therapy

Pronunciation American British Australian Indian
E.g.
  • This use is especially relevant to human gene therapy.
  • Two efforts being studied are the use stem cells and gene therapy.
  • Biotechnology has also enabled emerging therapeutics like gene therapy.

gene family

Pronunciation American British Australian Indian
E.g.
  • "SURF2" is a member of the surfeit gene family.
  • A gene cluster is part of a gene family.
  • The olfactory receptor gene family is the largest in the genome.

gene flow

Pronunciation American British Australian Indian
E.g.
  • There was some gene flow from Morocco into Iberia.
  • It is not known when gene flow between the subspecies ceased.
  • Residual gene flow between them (and between the two (or more?)

gene transfer

Pronunciation American British Australian Indian
E.g.
  • Horizontal gene transfer seems to be common among many microbes.
  • They also typically undergo low rates of horizontal gene transfer (HGT).
  • Endosymbiotic gene transfer is how we know about the lost chloroplasts in many CASH lineages.

gene is located

Pronunciation American British Australian Indian
E.g.
  • The gene is located on the q arm of chromosome 2.
  • The human "GATA1" gene is located on the short (i.e.
  • This gene is located on chromosome 1 at 1q31.1.

gene pool

Pronunciation American British Australian Indian
E.g.
  • With others, they amount up to around 20% of the gene pool.
  • It also reported an open pan- genome showing a vast diversity of the gene pool.
  • All organisms on Earth are descended from a common ancestor or ancestral gene pool.

gene product

Pronunciation American British Australian Indian
E.g.
  • "NF1" was cloned in 1990 and its gene product neurofibromin was identified in 1992.
  • It comprises 18 exons and spans 45 kb, and the protein gene product contains 839 amino acids in mature form.
  • Unlike single gene disorders, diseases caused by aneuploidy are the result of improper gene dosage, not nonfunctional gene product.

human gene

Pronunciation American British Australian Indian
E.g.
  • There are no paralogs of the human gene LOC100287387.
  • This use is especially relevant to human gene therapy.
  • This sequence is partially complementary to the human gene PCNX1.

gene regulation

Pronunciation American British Australian Indian
E.g.
  • This form of gene regulation is called enzyme induction.
  • C-rich DNA regions are common in gene regulation portions of the genome.
  • The effects of amphetamine on gene regulation are both dose- and route-dependent.
E.g.
  • It binds to nuclear receptors that regulates gene transcription.
  • al held that miRNAs display a pattern of up-regulation on gene transcription together with AGO2 and FXR1.
  • NamiRNAs are able to promote global gene transcription by binding their targeted enhancers in whole genome level.

gene encoding

Pronunciation American British Australian Indian
E.g.
  • The gene encoding neutrophil elastase, ELA2, consists of five exons.
  • In humans, a gene encoding INMT is determined to be located on chromosome 7.
  • Collagen, type XXII, alpha 1 COL22A1 is a human gene encoding for collagen.

receptor gene

Pronunciation American British Australian Indian
E.g.
  • The 5-HT receptor gene is found on the X-chromosome, Xq24.
  • The olfactory receptor gene family is the largest in the genome.
  • The V1a vasopressin receptor gene is a mechanism most widely studied.

gene cluster

Pronunciation American British Australian Indian
E.g.
  • The distance between each gene in the gene cluster can vary.
  • A gene cluster is part of a gene family.
  • In the case where a gene cluster is duplicated, some genes may be lost.

horizontal gene

Pronunciation American British Australian Indian
E.g.
  • They also typically undergo low rates of horizontal gene transfer (HGT).
  • There are concerns that horizontal gene transfer to other bacteria could have unknown effects.
  • The gene encoding the cholera toxin was introduced into "V. cholerae" by horizontal gene transfer.

gene products

Pronunciation American British Australian Indian
E.g.
  • "gli1" and "gli2" transcription is activated by Shh, and their gene products act as transcriptional activators for their own expression and for targets downstream of Shh signaling.
  • Ranaviruses are large icosahedral DNA viruses measuring approximately 150 nm in diameter with a large single linear dsDNA genome of roughly 105 kbp which codes for around 100 gene products.
  • The presence of the gene does not guarantee it will be expressed at appropriate levels in the target tissue so methods that look for and measure the gene products (RNA and protein) are also used.
E.g.
  • They also typically undergo low rates of horizontal gene transfer (HGT).
  • There are concerns that horizontal gene transfer to other bacteria could have unknown effects.
  • The gene encoding the cholera toxin was introduced into "V. cholerae" by horizontal gene transfer.

single gene

Pronunciation American British Australian Indian
E.g.
  • Each of the single gene defects is rare, with more than 200 in all described.
  • In bumblebees, sex is actually determined by a single gene locus with many alleles.
  • In its simplest form, Goodwin's oscillator involves a single gene that represses itself.

gene belongs

Pronunciation American British Australian Indian
E.g.
  • This gene belongs to the subfamily of small cytokine CC genes.
  • The protein encoded by this gene belongs to the EGR family of CysHis-type zinc finger proteins.
  • This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum.
E.g.
  • Mutations in this gene are associated with progressive myoclonic epilepsy type 5.
  • Mutations in the "PLEKHG5" gene are associated with distal spinal muscular atrophy type 4.
  • Some mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

gene mutations

Pronunciation American British Australian Indian
E.g.
  • She keeps a lab blog, where they document the important gene mutations they have discovered so far.
  • [10] Studies on SOX3 gene mutations have demonstrated that it plays a role in parathyroid development.
  • It is used for the treatment of cystic fibrosis (CF) in people six years and older, who have specific gene mutations.
E.g.
  • It postulates that gene clusters were formed as a result of gene duplication and divergence.
  • Ohno theorized that the origin of new genes during evolution was dependent on gene duplication.
  • When gene duplication occurs to produce a gene cluster, one or multiple genes may be duplicated at once.
E.g.
  • The olfactory receptor gene family is the largest in the genome.

defective gene

Pronunciation American British Australian Indian
E.g.
  • They have no symptoms but may pass down the defective gene to their children.
  • Since horses with only one copy of the defective gene were normal, the mutation was labeled "e" or sometimes "E".
  • Genetic engineering could potentially fix severe genetic disorders in humans by replacing the defective gene with a functioning one.
E.g.
  • The olfactory receptor gene family is the largest in the genome.

gene contains

Pronunciation American British Australian Indian
E.g.
  • In most people, Exon 3 of the gene contains a sequence of 20 polyalanine repeats.
  • The gene contains an open reading frame (ORF) of 8,133 nucleotides, coding for 2,710 amino acids.
  • The "CLU" gene contains nine exons and expresses three isoforms alternatively-spliced at the first exon.

gene on chromosome

Pronunciation American British Australian Indian
E.g.
  • It, in humans, is encoded by the "PGAM5" gene on chromosome 12.
  • In humans, clusterin is encoded by the "CLU" gene on chromosome 8.
  • Myeloperoxidase Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the "MPO" gene on chromosome 17.
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